Proteins perform a wide variety of functions in cells through interactions with each other and many additional molecules. These interactions are traditionally understood from a static description (a picture); however proteins are not static, on the contrary they change between multiple states (a movie). They move dynamically between these states (conformations) – our research is aimed elucidating the relation between dynamics, conformation and experimental (mostly NMR) data on proteins. By unravelling the underlying physical and chemical principles with statistics and informatics, and relating them to biological events, we try to better understand how proteins work, and generate new approaches that predict how they work – placing the research in the interdisciplinary structural bioinformatics or structural computational biology category.
See the Bio2Byte website for more information
Algorithms in computational biology and bioinformatics (VUB//ULB, titular)
Structural biology, NMR partims (VUB, co-titular)
General chemistry, 1st bachelor Biology/Geografy (VUB, co-titular)
Structural bioinformatics, NMR partim (ULB, co-titular)