New publication in Nature Communications
Researchers in Brussels, including Tom Lenaerts, Peter Tompa and Wim Vranken of the VUB, have developped an innovative method to predict a protein's strructural flexibility directly from its amino acid sequence. This publication is a first result produced by the new Interuniversity Institute for Bioinformatics IB2 (or IBsquare). The method allows for the analysis at genomic scale of the dynamic patterns of proteins without knowing their actual structure. This result provides a major breakthrough as dynamics are essential for understanding the function of proteins. As such this new methodology opens the door to a variety of innovative applications ranging from improved disorder prediction to the analysis of the evolutionary conservation of those dynamics.
More information in the journal itself via http://www.nature.com/ncomms/2013/131114/ncomms3741/full/ncomms3741.html